Prof Mehrotra is the CEO and Program Lead at the India Cancer Research Consortium affiliated to the Indian Council of Medical Research and an Adjunct Professorship of Epidemiology at the Rollins Institute of Public Health, Emory University, Atlanta, the York and Brunel Universities.  He sits on the Scientific Council of the International Agency for Research on Cancer (IARC-WHO), Lyon, France and an editorial board member of the Bluebooks on Cytology and Histopathology.  He has been the President of the Indian Academy of Cytologists. Till 2019, he led the ICMR-National Institute of Cancer Prevention and Research as well as the WHO-FCTC Global Hub on Smokeless Tobacco Products.

In addition to his stint in academia at various medical schools, Dr Mehrotra has led successful programs in epidemiology. Over and above his expertise in cancer prevention, epidemiology and pathology,  Prof Mehrotra has a wealth of experience leading large multi-disciplinary teams, overseeing operations, shaping and implementing national-scale strategic plans, fostering key institutional partnerships and using evidence to influence policy. Has extensive experience collaborating with leaders in government, academia, private and not-for-profit sectors and has facilitated collaborative projects with well-known international institutions such as the US National Institutes of Health, Centers for Disease Control and Prevention, National Institute of Health Research, UK, The Union and the World Health Organization- Framework Convention for Tobacco Control. He is an impactful researcher with nearly 300 peer-reviewed publications, including The Lancet, BMJ, JAMA and Nature, numerous books/chapters and technical reports, he sits on the editorial board of 8 medical journals and is the Principal Investigator of over 10 national and international research grants.  He is the winner of many prestigious awards, including the prestigious

Dr P.N.Wahi and Dr Lachman award in Cancer prevention as well as the Ernest Fernandes Award of the Indian Academy of Cytologists, in addition to being its past President.

Dr Mehrotra holds degrees in Medicine from the Armed Forces Medical College, Pune; MD and  DPhil from the University of Allahabad as well as the Fellowship of the Royal College of Pathology. He is interested in innovations in cancer prevention, tobacco control, frugal innovations and application of genomics in cancer diagnostics and decision-making.